Synerige Skin | A+

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An advanced vitamin A serum with the hero retinoid, hydroxypinacolone retinoate (HPR), and folic acid. This evening serum promotes healthy skin renewal, reverses visible signs of ageing and clarifies pores for smoother, clearer and brighter skin.

6% vitamin A complex with added folic acid

Regulates cell turnover for smooth, bright skin

Reduces fine lines and wrinkles by promoting collagen

Controls oil and acne breakouts

Reduces the appearance of hyperpigmentation and uneven skin tone

Use with Rejuvaderm Home Roller for optimal penetration

Key Ingredients

6% RetiGen Complex™ (Hydroxypinacolone retinoate, green tea, coenzyme 010) Proprietary retinoid blend: A powerful blend of skin perfecting ingredients with the cutting-edge hero retinoid, hydroxypinacolone retinoate, at the centre.

Hydroxypinacolone retinoate: This next generation vitamin A ingredient requires no metabolic conversion by the target cell in order to exert its numerous beneficial effects. Clinical studies demonstrate that hydroxypinacolone retinoate visibly reduces the appearance of lines and wrinkles in as little as 14 days, while also brightening clearing, firming and plumping the skin, reducing visible pores and normalising excess oil production.

Coenzyme Q10: Involved in numerous biological functions, including energy production and stabilising free radicals. Coenzyme 010 levels decrease with age resulting in a reduced ability to produce collagen and elastin. Topically applied, this ingredient assists in reversing and preventing the visible signs of ageing.

Green tea: A potent antioxidant that neutralises free radicals and prevents oxidative stress. Green tea is rich in polyphenols and epigallocatechin gallate, which inhibit elastase and matrix metalloproteinases (MMPs), responsible for the breakdown collagen and elastin. Green tea also inhibits the production of tyrosinase, a key enzyme involved in pigment production, thereby resulting in a brighter and more even complexion.

Folic acid: Folic acid has proven skin regeneration properties and can modulate and increase the rate of DNA repair in UV-damaged skin. Studies demonstrate folic acid's ability to revitalise fibroblast cells, which are responsible hyaluronic acid, collagen and elastin production. Folic acid also increases the skin's moisturisation and decreases transepidermal water loss (TEWL) without any significant change of sebum secretion.

Additional ingredients: Dimethyl isosorbide

HPR (Hydroxypinacolone Retinoate) is the most active and potent form of Vitamin A on the market right now, next only to prescription retinoids. Clinical studies demonstrate that HPR visibly reduces the appearance of fine lines and wrinkles in 14 days while also brightening, reducing acne breakouts, and normalising excess oil production. This ingredient truly is the new queen of Vitamin A.

Full Ingredient List
AQUA (PURE AUSTRALIAN RAINWATER), GLYCERIN, DIMETHYL ISOSORBIDE, ISOAMYL LAURATE, METHYLPROPANEDIOL, TOCOPHEROL (VITAMIN E), CAPRYLYL GLYCOL, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, HYDROXYPINACOLONE RETINOATE, FOLIC ACID, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, UBIQUINONE, CYMBOPOGON MARTINI (PALMAROSA) OIL, PHENYLPROPANOL, GLYCINE SOJA (SOYBEAN) OIL, SODIUM PHYTATE, 1,2-HEXANEDIOL, HYDROXYACETOPHENONE, ALCOHOL (GRAIN DERIVED), SODIUM HYDROXIDE, GERANIOL, LINALOOL, D-LIMONENE.

Apply one pump over face and neck. Always apply sparingly and monitor tolerance.

Always apply A+ sparingly and monitor tolerance. Start by using Ultimate A and advance to A+ after 3 to 6 months, alternating every evening over a 4 week period to gradually acclimatise to A+.

Order of Application
1. Cleanse AM/ PM
2. Prepare and balance AM/ PM
3. A+ and other serums PM
4. Eye care AM/ PM
5. Moisturise AM/ PM
6. Solar Protection AM

Synergie Skin is widely regarded by cosmetic medical practitioners and skin clinicians as a leading cosmeceutical range. Founded in 2005, and now an internationally recognised company,Synergie Skin is an innovative Australian cosmeceutical company committed to creating highly active skincare. Synergie offers both highly active cosmeceutical products and a medical only range, Synergie Practitioner, which formulas contain higher dosages of active ingredients and additional potent active ingredients. This range offers clients a step up from the Synergie Skin range and is exclusive to medically-affiliated practices.